Bioinformatician

Studies will be conducted focusing on the role of inhibitory pathways in dampeninib immune responses to tumors. Elaborate therapeutic strategies to reverse tumor-induced immune dysfunction to promote tumor regression in patients with advanced cancers.Responsibilities Include:Identification of novel major target of immunotherapy, TIGIT which is being investigated in multiple clinical trials by multiple pharmaceutical companies. Study the role of inhibitory pathways in dampeninib immune responses to tumors. Contribute to elaborate therapeutic strategies to reverse tumor-induced immune dysfunction to promote tumor regression in patients with advanced cancer. Collaborate in the preparation of, amendment, and renewal of relevant mouse protocols. Prepare and draft manuscripts related to the work. Assist in the generation of grant annual progress reports and updates. Similarly the individual will contribute to/assist the laboratory PI in the development of/preparation of new grant proposals. Supervising and training new members of the laboratory. Training of graduate students, clinical fellows, and undergraduates in the lab will be a significant role. The ability to be a member of the team and integrate is an important aspect of the position. In addition, maintenance of laboratory safety records, assisting in maintenance of laboratory freezers and inventory will be required.

Manages or assists with managing large, moderately complex projects or multiple, small projects related to biomedical informatics. Documents functional requirements and supervises project schedules, timelines, processes, workflow, and other parameters. Assists or manages projects from idea through implementation and adoption within budget, on time, and in scope.

Operation and maintenance of complex scientific instrumentation, computer competence, effective communication, handling of rodents, pathology collection.

Moderate activity required. Will frequently travel to various laboratories or animal faciltiies. Experiments are long and complex and require extended periods of standing or sitting and concentration.

The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community. This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover, belong, contribute, and grow, while honoring the experiences, perspectives, and unique identities of all.

The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets.