Post Doctoral Fellow -Cell Biology and Physiology
University of Kansas Medical Center
Kansas City, KS
Full-time
Education
Posted on May 18, 2024
Post Doctoral Fellow -Cell Biology and Physiology
Department:
SOM KC Division of Molecular and Integrative Physiology
-----
Waugh Lab
Position Title:
Post Doctoral Fellow -Cell Biology and Physiology
Job Family Group:
Professional Staff
Job Description Summary:
A Post-Doctoral Fellowship is immediately available at the University of Kansas Medical Center (KUMC) in Kansas City, KS under the direct mentorship of principal investigator (PI) Katherine A. Waugh PhD, an Assistant Professor in the Department of Cell Biology and Physiology (CBP). This is a full-time salaried position that will occasionally necessitate work during evenings and weekends. Salary range is $50,000 - 65,000, commensurate with skills, experience, and available laboratory funds.
Individuals passionate about relevant biomedical research are encouraged to apply. An overview of the research program can be found on following the laboratory website: https://www.kumc.edu/kwaugh.html and includes keywords of inflammation, maternal immune activation, placenta, Down syndrome, as well as “developmental origins of health and disease.”
Within this research program, the Post-Doctoral Fellow will spearhead incorporation of placenta studies into our broader research program. More specifically, the selected candidate will join a multidisciplinary team in a highly collaborative environment to drive development of projects that relate to the placenta using diverse human and animal model systems to translationally pursue maternal immune activation and Down syndrome (details below).
The nature of this work therefore requires a willingness to perform animal research responsibly and respectfully, including but not limited to mouse husbandry, handling, injections, oral gavage, imaging, cognition/behavior assays, euthanasia, and tissue collection.
Lastly, this laboratory is housed in a modern research space with access to state-of-the-art equipment and will build on a long history of innovative service to the KUMC community.
Job Description:
Required Qualifications
Education: PhD degree or equivalent doctoral degree in molecular biology, developmental biology, physiology, immunology, or related scientific field.
Work Experience:
- Minimum of four 4 years of related experience.
- Demonstrated ability to function as a team player in a matrixed environment, including a strong track record of mentoring junior colleagues.
- Project management, as demonstrated by publication track record.
- Proven ability to perform animal research responsibly and respectively, such as mouse husbandry, handling, and euthanasia.
- Experience integrating of primary human samples and clinical data to build on basic research projects.
- Background in molecular biology, including experience querying gene-expression and protein abundance (e.g., RT-PCR, ELISA).
- Experience with sterile technique (e.g., tissue culture of human trophoblasts).
- Previous development of standard operating procedures through literature searches.
Preferred Qualifications
Education: PhD degree or equivalent doctoral degree in molecular biology, developmental biology, physiology, immunology, or related scientific field AND prior experience as a Postdoctoral Fellow.
Work Experience:
- Minimum of five (5) years of related experience that includes mentoring junior colleagues.
- Experience in Down syndrome research.
- Demonstrated ability to learn, operate, and troubleshoot complex laboratory equipment.
- A demonstrated proclivity towards improving processes and delivering practical solutions.
- Track record of assembling, revising, and successfully publishing scientific manuscripts on topics specifically related to this position.
- Previous experience verbally disseminating scientific results at meetings and conferences.
- Previous experience competing for research funds via grant mechanisms.
- History of initiating then maintaining productive scientific collaborations.
- Strong track record in murine research, such as husbandry, handling, i.p. and i.v. injections, oral gavage, imaging, cognition and behavioral assays, euthanasia, and tissue collection (e.g., blood from live animals and embryos following animal sacrifice).
- Extensive experience designing then executing complementary assays to study the placenta using human samples, such as trophoblast isolation from first trimester placental tissue, explant culture, and organoid culture.
- Strong background in molecular biology, including experience with high-throughput methods to query gene-expression and protein abundance (e.g., RNA-seq, Cut & RUN, and ChIP-seq).
- Laboratory experience with the following: human maternal and cord blood fractionation for characterization of immune subsets and biomarkers of inflammatory states; molecular, morphological, and histological evaluation of the human and mouse placentas.
Skills:
- Effective written and oral communication skills.
- Strong quantitative analysis skills, including a solid foundation in statistics.
- Excellent organizational skills for multi-tasking in a laboratory setting.
- Ability to learn new techniques to pursue novel concepts.
Job Duties Outlined:
- Participate in regular communication with the PI and colleagues via both group laboratory and one-on-one meetings.
- Actively participate in career development activities available at KUMC for Postdoctoral Fellows.
- Organized record keeping of research.
- Spearhead the creative design, execution, and analysis of complementary in vitro experiments using mouse and human cells/tissues within a multidisciplinary team setting (e.g., ‘placentomics' of primary human samples).
- Spearhead cause-effect experiments using mouse models within a team setting to define the in vivo impacts of maternal immune activation on the placenta as a mediator of the heterogeneous health and cognitive function among individuals with trisomy 21.
- Collect, analyze, and interpret data for planning of future experiments, resultant publications, and grant applications.
- Work directly with the PI to prepare manuscripts for publication in scientific journals based on experimental results, as well as to write reviews on related topics.
- Work directly with the PI to prepare grant applications in support of both individual career development and team laboratory funding.
- Actively participate in the dissemination of results by presenting to both the scientific and general audiences from local to international forums.
- Participate in routine laboratory and animal model maintenance.
- Perform other duties as assigned within the scope of this fellowship.
Required Documents:
- Resume/CV
- Cover Letter
Comprehensive Benefits Package:
Coverage begins on day one for health, dental, and vision insurance and includes health expense accounts with generous employer contributions if the employee participates in a qualifying health plan. Employer-paid life insurance, long-term disability insurance, and various additional voluntary insurance plans are available. Paid time off, including vacation and sick, begins accruing upon hire, plus ten paid holidays. One paid discretionary day is available after six months of employment, and paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment. A retirement program with a generous employer contribution and additional voluntary retirement programs (457 or 403b) are available. https://www.kumc.edu/human-resources/benefits.html
Employee Type:
Regular
Time Type:
Full time
Rate Type:
Salary
Compensation Statement:
The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above.
Pay Range:
$47,476.00 - $80,000.00
Minimum
$47,476.00
Midpoint
$66,000.00
Maximum
$80,000.00
Application Instructions:
To learn more and apply online, please visit https://kumc.wd5.myworkdayjobs.com/en-US/kumc-jobs/job/Kansas-City-Metro-Area/Post-Doctoral-Fellow--Cell-Biology-and-Physiology_JR007070 or go to https://careers.kumc.edu/ and search for position number JR007070.
Applications must be submitted directly through the KU Medical Center website to be considered for this position. Any applications submitted via email or this website will NOT be reviewed or considered.
About KU Medical Center:
The University of Kansas Medical Center’s mission is to educate exceptional health care professionals through a full range of undergraduate, graduate, professional, postdoctoral and continuing education programs in the schools of Medicine, Nursing and Health Professions. KU Medical Center also advances the health sciences through world-class research programs; provides compassionate and state-of-the-art patient care in an academic medical center environment; and works with communities in every Kansas county to improve the health of Kansans. Learn more at www.kumc.edu.
Benefits:
KUMC offers a range of great benefits that support employees and eligible family members. Our health insurance benefits begin on hire date and KUMC offers other exciting benefits such as paid parental leave, generous employer retirement contributions and other resources to improve health and well-being. For more information, please visit https://www.kumc.edu/human-resources/benefits.html
Equal Employment Opportunity Statement
The University of Kansas Medical Center is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, ethnicity, ancestry, age, protected veteran or disability status, marital status, parental status, or genetic information. http://policy.ku.edu/IOA/nondiscrimination
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